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Lack of Mannose-Binding Lectin Decreases Immunity

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December 04, 2014

by Case Adams, Naturopath

(GreenMedInfo.com) In a recent article, I discussed some of the history regarding the Ebola virus and the fact that contracting Ebola – like many other viruses – requires not simply contact with a symptomatic patient, but an immune system unable to defend itself against the virus.

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This lack of defense can come in the form of immunosuppression, but it can also come from a deficient production of mannose-binding lectins, which may well be the result of a poor diet or other stress factors that erodes the immune system.

As investigators have found over the past decade of research on not just viruses, but many other infectious diseases, part of immunosuppression comes in the form of a lack of production of mannose-binding lectins (MBLs).

These natural biochemicals are produced by a healthy immune system and they have the distinction of being able to break apart glycoproteins that cover many viruses, as well as certain bacteria and yeasts.

Some of these dangerous microbes use these glycoprotein envelopes to protect themselves from the immune system, and to help them penetrate cell membranes – which also have glycoproteins in their membranes.

As such a glycoprotein enveloped virus or microorganism penetrates the cell membrane, it can wreck its havoc upon the cell.

Viruses do this by inserting genetic information that hijacks the DNA and RNA of the cell – making the cell a clone for the virus to replicate.
Mannose-Binding Lectin Deficiencies Implicated In Many Diseases

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