November 15, 2016
(GreenMedInfo.com) We know that all drugs have side effects. That’s just part of the deal right? But is it really possible that an antidepressant can cause a sane person to act like a cold-blooded criminal?
I imagined my audience would be wondering as much as I arrived to an unseasonably chilly day at King’s College in London. I was there to share what I have learned about the medications that I so dutifully and faithfully prescribed during the early part of my career, and also about the deep potential for healing depression in simple, safe ways, according to the latest science.
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The day before my flight, I had received an email from a man who I would choose to invite on stage with me that day. His name is David Carmichael and he wrote:
“I took the life of my 11-year-old son Ian on July 31, 2004 in a Paxil-induced state of psychosis and was charged with first degree murder. I was judged to be “not criminally responsible on account of a mental disorder” in September 2005 and received an absolute discharge from the forensic psychiatric system (in Ontario, Canada) in December 2009. I’ve been off all prescription drugs since September 2010. Prior to our family tragedy, I was a physical active sports consultant with no history of violence or mental illness.”
He told an audience of clinicians and patients, that day, about how it is that a normal citizen, prescribed a seemingly safe medication for work-related stress, goes on to commit a heinous act of violence against his beloved child. This academic classroom was heaving with grief when he finished his description of events.
This must be rare, right? Totally anomalous?
Wrong.
It has become my contention that the Russian Roulette that is played with each new prescription of psychotropic medication violates the physician’s most primal tenet – first do no harm – and does so in the absence of anything approximating informed consent.
Violence as a Side Effect?
Thankfully, we are often given multiple chances to wake up to a greater truth. It’s becoming easier than ever. With grassroots platforms like madinamerica.com, the information is out there, when you are ready to look beyond main stream media to what the real victims are claiming.
The truth about antidepressants and violence is also in the most recently published literature, including a critical review, hot off the press, by Carvalho et al where the authors dive into the research on the supposed safety of SSRIs and SNRIs. In this document, they present an evidence-based horror menagerie of ways in which a simple antidepressant can derail your life if it doesn’t take it. Leaving patients with new medical diagnoses, antidepressants prescribed often for difficult transitions in life like divorces and deaths, carry documented risks that your doctor cannot possibly tell you about because if they knew of them, they would put down their prescription pad immediately.
Let’s take a tour. Neatly summarized here, the adverse effects of antidepressants can sound like that droning voice in TV ads that we are inured to because we have been told these “side effects are rare, and outweighed by the benefits.”
But the benefits are shockingly limited so, let’s take a closer look at those side effects…
The Risks That Made Me Quit Prescribing
Having always represented antidepressants as safe and effective to my patients, I put down my prescription pad after learning 3 facts about psychiatric medications:
- They result in worse long-term outcomes [1]
- They are debilitatingly habit forming [2] [3] [4]
- They cause unpredictable violence [5] [6]
These insights were apparently just the tip of the iceberg. Several years into the horror stories of patient experiences and new relationships with grassroots activists, I am left wondering. What on earth are these meds? How could biochemistry have ever manifested molecules capable of derailing, distorting, and suppressing the human experience to this extent?
With more unknowns than knowns at this point, the signal of harm is growing and patient alignment with this model of care, diminishing.
I pulled some choice phrases from the paper for your further enlightenment below but suffice it to say that many of these side effects are major gamechanging problems if not life-ending tragedies that render the placebo-level performance of these medications totally unacceptable.
Gut disturbance: “Some of the most frequently reported side effects associated with the use of SSRIs and serotonin noradrenaline reuptake inhibitors (SNRIs) include nausea, diarrhea, dyspepsia, GI bleeding and abdominal pain.”
Liver toxicity: “Two main mechanisms may be involved in antidepressant- induced liver toxicity, namely a metabolic component and/or an immuno-allergic pathway. A hypersensitivity syndrome with fever and rash as clinical manifestations, as well as with autoantibodies and eosinophilia, and a short latency period (1–6 weeks) point to a predominantly immunoallergic pathophysiological mechanism, whereas a lack of hypersensitivity syndrome and a longer latency period (i.e. 1 month to 1 year) points to an idiosyncratic metabolic mechanism.”
Weight gain: “Notwithstanding the complexity of the clinical scenario, compelling evidence indicates that the use of most antidepressants may increase weight in a significant proportion of patients.”
Heart problems: “SSRIs and SNRIs may promote a decrement in heart rate variability (HRV). Although the impact of the effects of antidepressants on HRV remains to be established, data indicate that a lower HRV is a significant predictor of incident cardiovascular events.”
Dr. Brogan is boarded in Psychiatry/Psychosomatic Medicine/Reproductive Psychiatry and Integrative Holistic Medicine, and practices Functional Medicine, a root-cause approach to illness as a manifestation of multiple-interrelated systems. After studying Cognitive Neuroscience at M.I.T., and receiving her M.D. from Cornell University, she completed her residency and fellowship at Bellevue/NYU. She is one of the nation’s only physicians with perinatal psychiatric training who takes a holistic evidence-based approach in the care of patients with a focus on environmental medicine and nutrition. She is also a mom of two, and an active supporter of women’s birth experience. She is the Medical Director for Fearless Parent, and an advisory board member for GreenMedInfo.com. Visit her website.
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