February2, 2015
by Barbara Minton
(The Best Years in Life) Would you like to have the brainpower you had 10, 20 or even 40 years ago? Research says it’s quite possible that a combo of acetyl L-carnitine and lipoic acid can restore cognitive ability to what it was in your prime.
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It all started with a landmark study back in 2008. Study director Bruce Ames found that old lab rats given a combination of acetyl L-carnitine and alpha-lipoic acid regained so much of their youth and vigor they “got up to do the Macarena”. Since then other research has confirmed Ames’ findings and found even more ways in which these two compounds can turn back the clock.
Free radicals and aging
Current thinking says aging is a product of free radical damage to cells and the DNA housed in them. Free radicals are atoms or molecules with a single unpaired electron in the outer shell. Most of them are highly reactive, bouncing around in the body and wrecking havoc until their unpaired electrons find a partner. In the process, oxidative damage occurs which produces the signs of what we call aging, and antioxidants limit this oxidative damage. Think of oxidation as leaving bare metal out in the rain, and antioxidants as a barrier between the metal and water.
This theory was first proposed in the 1950’s, and in the 1970’s it was extended to implicate mitochondrial production of free radicals. As a theory, it has not been successfully challenged in all these years.
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